WEBVTT 1 00:00:02.354 --> 00:00:04.937 (upbeat music) 2 00:00:13.050 --> 00:00:14.380 Welcome everyone. 3 00:00:14.380 --> 00:00:16.260 We're so glad you can join us today. 4 00:00:16.260 --> 00:00:19.290 We have an outstanding CEO discussion planned, 5 00:00:19.290 --> 00:00:22.800 and we're honored and excited to have Giovanni Caforio, 6 00:00:22.800 --> 00:00:24.780 CEO of Bristol Myers Squibb, 7 00:00:24.780 --> 00:00:28.540 and Kevin Sayer, CEO of Dexcom, as our panelists. 8 00:00:28.540 --> 00:00:29.770 During today's session, 9 00:00:29.770 --> 00:00:33.050 Giovanni and Kevin will share their perspectives 10 00:00:33.050 --> 00:00:36.200 on the 2022 health care industry outlook. 11 00:00:36.200 --> 00:00:39.163 It promises to be an engaging and insightful session. 12 00:00:40.040 --> 00:00:43.030 (upbeat music) 13 00:00:43.030 --> 00:00:44.770 I think it has changed 14 00:00:44.770 --> 00:00:46.380 the way we think about drug development, 15 00:00:46.380 --> 00:00:49.350 because when you think about developing a vaccine 16 00:00:49.350 --> 00:00:51.016 in one year, of course, the pandemic created an incredible sense of urgency 17 00:00:51.016 --> 00:00:54.849 and the teams that worked did a fantastic job, 18 00:00:57.430 --> 00:01:00.477 but it's impossible for me to then go back and say, 19 00:01:00.477 --> 00:01:02.750 "Let's go back to taking ten years 20 00:01:02.750 --> 00:01:03.967 to develop the next cancer medicines." 21 00:01:03.967 --> 00:01:06.680 With respect to the providers, 22 00:01:06.680 --> 00:01:08.890 during the COVID times in particular, 23 00:01:08.890 --> 00:01:12.380 we have been able to introduce an element of telemedicine 24 00:01:12.380 --> 00:01:15.230 with our data in the Cloud and our connected devices 25 00:01:15.230 --> 00:01:17.290 to whereby diabetes treatment, 26 00:01:17.290 --> 00:01:20.960 for patients on Dexcom system became very natural, 27 00:01:20.960 --> 00:01:22.440 in a telemedicine environment. 28 00:01:22.440 --> 00:01:24.680 We have an imperative to do things differently, 29 00:01:24.680 --> 00:01:26.890 and I think there is a real opportunity. 30 00:01:26.890 --> 00:01:29.930 We've learned how technology accelerates 31 00:01:29.930 --> 00:01:33.470 the development of medicines by making clinical trials 32 00:01:33.470 --> 00:01:38.470 easier to monitor by eliminating some of the maybe visits, 33 00:01:38.950 --> 00:01:42.620 or tests that we were doing that weren't necessary. 34 00:01:42.620 --> 00:01:47.620 We've exchanged data with regulators on a continuous basis. 35 00:01:48.090 --> 00:01:50.550 In many cases, we've seen institutions and governments 36 00:01:50.550 --> 00:01:52.290 being willing to work with us, 37 00:01:52.290 --> 00:01:57.000 in very, very different ways and exchange perspectives live. 38 00:01:57.000 --> 00:02:00.520 In the FDA with Dexcom, in particular, over time 39 00:02:00.520 --> 00:02:02.930 it's been a very good relationship, 40 00:02:02.930 --> 00:02:06.450 and it's based on a very simple concept here, 41 00:02:06.450 --> 00:02:09.560 we talk to them and had a partnership before we start, 42 00:02:09.560 --> 00:02:12.280 "This is what we're going to do, how we're going to do it." 43 00:02:12.280 --> 00:02:14.000 And when we do what we say we're going to do, 44 00:02:14.000 --> 00:02:15.233 things go very well. 45 00:02:16.196 --> 00:02:18.779 (upbeat music) 46 00:02:20.070 --> 00:02:23.560 You know, we have over 85 important partnerships 47 00:02:23.560 --> 00:02:25.890 with biotech companies, with academia, 48 00:02:25.890 --> 00:02:29.140 where we are advancing programs together. 49 00:02:29.140 --> 00:02:30.830 And it's really the core, as I said, 50 00:02:30.830 --> 00:02:33.360 of the innovation strategy of BMS. 51 00:02:33.360 --> 00:02:35.490 I think from my perspective, 52 00:02:35.490 --> 00:02:37.730 it requires us to be really open 53 00:02:37.730 --> 00:02:40.690 of people that may be thinking about science 54 00:02:40.690 --> 00:02:41.940 differently than you. 55 00:02:41.940 --> 00:02:44.760 It requires building a very high degree of the trust, 56 00:02:44.760 --> 00:02:48.090 a level of transparency with your partner. 57 00:02:48.090 --> 00:02:51.740 And what makes it easy in our case 58 00:02:51.740 --> 00:02:53.100 is that we have a common goal, 59 00:02:53.100 --> 00:02:55.210 you know, we know we have a patient 60 00:02:55.210 --> 00:02:58.150 that is waiting for a very different treatment option 61 00:02:58.150 --> 00:02:59.560 for a very serious disease. 62 00:02:59.560 --> 00:03:02.350 And that brings different teams together 63 00:03:02.350 --> 00:03:03.610 in a very, very unique way. 64 00:03:03.610 --> 00:03:06.270 What we hear from the companies we work with, 65 00:03:06.270 --> 00:03:08.840 is the desire to be doing work together, 66 00:03:08.840 --> 00:03:10.130 and advance a common mission, 67 00:03:10.130 --> 00:03:12.190 because obviously there is a lot of passion 68 00:03:12.190 --> 00:03:14.270 for what's been invented 69 00:03:14.270 --> 00:03:17.610 in a startup, in a small biotech company. 70 00:03:17.610 --> 00:03:21.420 And we don't take the approach of being the large pharma 71 00:03:21.420 --> 00:03:24.400 that comes to the table, 72 00:03:24.400 --> 00:03:25.760 you know, we take the approach 73 00:03:25.760 --> 00:03:28.550 of being a true committed partner 74 00:03:28.550 --> 00:03:32.921 that will work with transparency and build trust over time. 75 00:03:32.921 --> 00:03:35.340 (upbeat music) 76 00:03:35.340 --> 00:03:38.320 Health equity has always obviously been a huge issue, 77 00:03:38.320 --> 00:03:40.750 but I think Covid really did shine a light 78 00:03:40.750 --> 00:03:42.290 on disparities in care. 79 00:03:42.290 --> 00:03:45.513 So let me ask, you Kevin first, and then Giovanni, 80 00:03:46.550 --> 00:03:48.130 you know, in the diabetes field, 81 00:03:48.130 --> 00:03:51.640 disparities in care, I think play a massive role. 82 00:03:51.640 --> 00:03:53.730 How does Dexcom think about it? 83 00:03:53.730 --> 00:03:56.060 What is your approach to addressing it? 84 00:03:56.060 --> 00:03:58.700 And what advice do you have for others? 85 00:03:58.700 --> 00:04:01.360 We actually did some research and some surveys on this, 86 00:04:01.360 --> 00:04:06.360 and we found there's great disparities in CGM usage, 87 00:04:06.470 --> 00:04:09.600 even when reimbursement is the same, 88 00:04:09.600 --> 00:04:13.273 there's disparities in usage of our devices, 89 00:04:14.660 --> 00:04:17.020 yet everybody, like in the medicare population, 90 00:04:17.020 --> 00:04:19.717 everybody's eligible, everybody's covered. 91 00:04:19.717 --> 00:04:22.460 We saw that at the beginning of the pandemic, 92 00:04:22.460 --> 00:04:24.299 we became really concerned 93 00:04:24.299 --> 00:04:28.470 that patients would lose access to important therapies. 94 00:04:28.470 --> 00:04:31.690 You know, we were right at the beginning of the pandemic. 95 00:04:31.690 --> 00:04:33.080 We made a decision, for example, 96 00:04:33.080 --> 00:04:37.010 for any patient that lost their health care insurance, 97 00:04:37.010 --> 00:04:39.470 because they lost their job due to the pandemic. 98 00:04:39.470 --> 00:04:43.040 We made all BMS medicines available for free 99 00:04:43.040 --> 00:04:44.710 to patients in the United States. 100 00:04:44.710 --> 00:04:45.830 Well, when we run studies, 101 00:04:45.830 --> 00:04:48.010 we run studies across the board, 102 00:04:48.010 --> 00:04:50.650 age, education, gender, ethnicity, everything, 103 00:04:50.650 --> 00:04:53.640 we try to include every single group 104 00:04:53.640 --> 00:04:57.310 when we're developing evidence to support the product. 105 00:04:57.310 --> 00:05:00.580 I think the one area that we've decided 106 00:05:00.580 --> 00:05:02.430 to really take leadership position in, 107 00:05:02.430 --> 00:05:05.250 is the area of the diversity in clinical trials, 108 00:05:05.250 --> 00:05:08.660 because ultimately I think it's really important 109 00:05:08.660 --> 00:05:11.960 to build trust in every community 110 00:05:11.960 --> 00:05:13.950 for what a new medicine, 111 00:05:13.950 --> 00:05:16.650 or a new therapeutic approach can do. 112 00:05:16.650 --> 00:05:21.090 And so we're investing significantly to make sure 113 00:05:21.090 --> 00:05:25.190 that we have a diversity of geographic location, 114 00:05:25.190 --> 00:05:27.880 clinical trial investigators, and of course, 115 00:05:27.880 --> 00:05:29.670 patients in clinical trials. 116 00:05:29.670 --> 00:05:30.840 The last piece I'll tell you 117 00:05:30.840 --> 00:05:33.190 is just driving access in those communities. 118 00:05:33.190 --> 00:05:35.840 The last piece of the world to reimburse for our system 119 00:05:35.840 --> 00:05:37.710 has been the Medicaid plans, 120 00:05:37.710 --> 00:05:41.520 and we've gone from zero Medicaid plans four years ago, 121 00:05:41.520 --> 00:05:45.404 to 45 of the 50 states now cover us. 122 00:05:45.404 --> 00:05:47.987 (upbeat music) 123 00:05:49.210 --> 00:05:50.470 We are increasingly focused 124 00:05:50.470 --> 00:05:53.050 on the role we can play as a large company. 125 00:05:53.050 --> 00:05:55.090 And it's for a number of reasons. 126 00:05:55.090 --> 00:05:57.110 First of all, you know, we are a health care company. 127 00:05:57.110 --> 00:06:01.140 So ultimately I think the health populations, 128 00:06:01.140 --> 00:06:06.140 the health of our customers is important, 129 00:06:06.203 --> 00:06:08.960 and is impacted by the choices we make on the environment. 130 00:06:08.960 --> 00:06:10.810 Second is because that's what our workforce 131 00:06:10.810 --> 00:06:11.800 is asking us to do. 132 00:06:11.800 --> 00:06:15.702 It's become an integrated element in product design, 133 00:06:15.702 --> 00:06:19.420 in our migration from G6 to G7, 134 00:06:19.420 --> 00:06:22.510 we're significantly decreasing the footprint of our device. 135 00:06:22.510 --> 00:06:24.240 There's much less plastic, 136 00:06:24.240 --> 00:06:25.190 there's much less size, 137 00:06:25.190 --> 00:06:27.020 there's much less to throw away. 138 00:06:27.020 --> 00:06:29.060 You know, when you start down this path, 139 00:06:29.060 --> 00:06:30.720 it's kind of the last thing on your mind, 140 00:06:30.720 --> 00:06:31.800 because what you really need to do, 141 00:06:31.800 --> 00:06:34.790 is just get the thing to work, you know? 142 00:06:34.790 --> 00:06:36.400 And get the technology out there, 143 00:06:36.400 --> 00:06:38.137 and get it developed up, and you wake up and say, 144 00:06:38.137 --> 00:06:41.280 "OK, how do we change our footprint going forward? 145 00:06:41.280 --> 00:06:42.780 How do we use less plastic? 146 00:06:42.780 --> 00:06:44.924 How do we recycle more?" 147 00:06:44.924 --> 00:06:47.507 (upbeat music) 148 00:06:48.520 --> 00:06:52.260 I think it's the number one, you know, priority. 149 00:06:52.260 --> 00:06:56.340 And it has changed so much over the last two years. 150 00:06:56.340 --> 00:06:58.590 You know, attrition rates have gone up, 151 00:06:58.590 --> 00:07:03.430 expectations have changed significantly in the workforce. 152 00:07:03.430 --> 00:07:05.840 I think for us, it really starts 153 00:07:05.840 --> 00:07:08.920 with highlighting the mission of the company, 154 00:07:08.920 --> 00:07:13.590 and being a patient-centric organization 155 00:07:13.590 --> 00:07:16.300 that really focuses on doing what's best for patients. 156 00:07:16.300 --> 00:07:19.070 That resonates with many scientists, 157 00:07:19.070 --> 00:07:21.160 and resonates with our workforce. 158 00:07:21.160 --> 00:07:26.160 Mission-driven recruitment has really been a theme for us, 159 00:07:27.908 --> 00:07:29.180 as we hire talent, 160 00:07:29.180 --> 00:07:31.761 and they hear from people who use our product. 161 00:07:31.761 --> 00:07:33.960 It's very easy to get people to come that way, 162 00:07:33.960 --> 00:07:35.770 but we're in a different age now, 163 00:07:35.770 --> 00:07:37.782 we're not competing with just other 164 00:07:37.782 --> 00:07:40.760 health care mission-driven companies. 165 00:07:40.760 --> 00:07:42.880 We're now competing with the tech giants 166 00:07:42.880 --> 00:07:44.210 for software programmers, 167 00:07:44.210 --> 00:07:46.250 and for electrical engineers, 168 00:07:46.250 --> 00:07:47.600 and things of that nature. 169 00:07:47.600 --> 00:07:49.400 We've got to grow and develop people, 170 00:07:50.950 --> 00:07:52.530 and create development programs 171 00:07:52.530 --> 00:07:53.610 that we haven't done in the past. 172 00:07:53.610 --> 00:07:57.180 And so we're working very hard on infrastructure 173 00:07:57.180 --> 00:07:59.433 to make people successful. 174 00:07:59.433 --> 00:08:02.016 (upbeat music) 175 00:08:03.164 --> 00:08:04.310 You know, we were the first company 176 00:08:04.310 --> 00:08:06.330 to share data with others, 177 00:08:06.330 --> 00:08:09.800 to enable people to see how somebody's doing. 178 00:08:09.800 --> 00:08:12.160 So we try and give our users the data 179 00:08:12.160 --> 00:08:14.800 where they can use it to best be successful, 180 00:08:14.800 --> 00:08:16.270 and it's complicated, 181 00:08:16.270 --> 00:08:19.560 but it really makes coming to work every day 182 00:08:19.560 --> 00:08:21.290 extremely rewarding. 183 00:08:21.290 --> 00:08:24.570 But our approach is going to be open architecture. 184 00:08:24.570 --> 00:08:27.600 If a user wants their data displayed in a different way 185 00:08:27.600 --> 00:08:31.350 than we display it, let's figure out a way to get there. 186 00:08:31.350 --> 00:08:34.740 And there we're providing numerous options for that. 187 00:08:34.740 --> 00:08:36.210 We integrate with insulin pumps 188 00:08:36.210 --> 00:08:38.050 for automated insulin delivery. 189 00:08:38.050 --> 00:08:41.970 We integrate with insulin pens with Bluetooth signals, 190 00:08:41.970 --> 00:08:45.230 integrate with all sorts of different entities 191 00:08:45.230 --> 00:08:46.600 to get the data where it needs to be. 192 00:08:46.600 --> 00:08:48.190 During the pandemic at BMS, 193 00:08:48.190 --> 00:08:50.550 we have launched six new medicines. 194 00:08:50.550 --> 00:08:54.170 And in many cases, these are very different ways 195 00:08:54.170 --> 00:08:56.470 of treating serious diseases 196 00:08:56.470 --> 00:08:58.930 versus what physicians and patients were used to. 197 00:08:58.930 --> 00:09:00.720 We've made a number of investments 198 00:09:00.720 --> 00:09:04.070 to have digital platforms to interact with customers. 199 00:09:04.070 --> 00:09:06.100 And I think we've demonstrated 200 00:09:06.100 --> 00:09:10.180 that it is possible to develop a very effective 201 00:09:11.420 --> 00:09:15.190 relationship, digitally, with health care providers, 202 00:09:15.190 --> 00:09:16.493 with prescribers, 203 00:09:16.493 --> 00:09:19.670 and help them understand the new treatment option, 204 00:09:19.670 --> 00:09:20.580 adopt a new medicine, 205 00:09:20.580 --> 00:09:24.300 because those launches actually have been very successful. 206 00:09:24.300 --> 00:09:29.300 There are many more software solutions coming digitally 207 00:09:29.370 --> 00:09:30.950 to help people manage those 208 00:09:30.950 --> 00:09:32.370 who are taking intensive insulin. 209 00:09:32.370 --> 00:09:35.130 As I look at the rest of the diabetes world, though, 210 00:09:35.130 --> 00:09:36.010 the Type 2 side, 211 00:09:36.010 --> 00:09:40.310 I'm very excited to get CGM out into that population, 212 00:09:40.310 --> 00:09:42.874 to whereby they have data to make decisions. 213 00:09:42.874 --> 00:09:45.800 (upbeat music) 214 00:09:45.800 --> 00:09:47.470 It's what we're all about. 215 00:09:47.470 --> 00:09:49.670 We have two-year-olds on the device. 216 00:09:49.670 --> 00:09:52.120 we have 95-year-olds on the device. 217 00:09:52.120 --> 00:09:54.150 Completely different experiences. 218 00:09:54.150 --> 00:09:57.800 So personalization is absolutely coming with what we do, 219 00:09:57.800 --> 00:10:00.080 and we can do that through software, 220 00:10:00.080 --> 00:10:02.320 and then through also interaction with the data 221 00:10:02.320 --> 00:10:05.150 that we take to the Cloud and we can share with others. 222 00:10:05.150 --> 00:10:08.830 So, I think not only is it part of our business today, 223 00:10:08.830 --> 00:10:11.060 it's going to be an even bigger part in the future. 224 00:10:11.060 --> 00:10:12.540 And that's how we'll continue to grow. 225 00:10:12.540 --> 00:10:14.400 We are not yet at the stage 226 00:10:14.400 --> 00:10:18.390 that we have a deep interaction with individual patients 227 00:10:18.390 --> 00:10:19.900 on their treatment choice. 228 00:10:19.900 --> 00:10:21.600 Although, I think we'll get there. 229 00:10:21.600 --> 00:10:25.430 I think where the way we think about personalized therapies 230 00:10:25.430 --> 00:10:28.130 is really to develop the right treatment approach 231 00:10:28.130 --> 00:10:29.870 for every single patient, 232 00:10:29.870 --> 00:10:31.940 which is a combination of different medicines 233 00:10:31.940 --> 00:10:33.910 at a different stage in their disease. 234 00:10:33.910 --> 00:10:37.330 Sometimes the integration between radiotherapy, 235 00:10:37.330 --> 00:10:42.080 surgery, and pharmaceutical interventions. 236 00:10:42.080 --> 00:10:43.580 And I think that's tailored 237 00:10:43.580 --> 00:10:45.140 to every single individual patient. 238 00:10:45.140 --> 00:10:48.150 Ultimately, I guess, you know, 239 00:10:48.150 --> 00:10:51.983 the future is connecting the person 240 00:10:53.550 --> 00:10:58.310 and the institution that is treating the patient, with us, 241 00:10:58.310 --> 00:11:02.910 to be able to understand what treatment 242 00:11:02.910 --> 00:11:07.274 is the best treatment for that patient, based on data. 243 00:11:07.274 --> 00:11:09.857 (upbeat music)